Publications
Jacky Guy, Hélène Cheval, Jim Selfridge, and Adrian Bird.The Role of MeCP2 in the Brain. Annual Review of Cell and Developmental Biology. Vol. 27: 631-652. PubMed Abstract
Deaton AM, Bird A.(2011). CpG islands and the regulation of transcription. Genes Dev. 25(10):1010-22. PubMed Abstract
Illingworth RS, Gruenewald-Schneider U, Webb S, Kerr AR, James KD, Turner DJ, Smith C, Harrison DJ, Andrews R, Bird AP. (2010). Orphan CpG islands identify numerous conserved promoters in the mammalian genome. PLoS Genet. 6(9). pii: e1001134. PubMed Abstract
Thomson JP, Skene PJ, Selfridge J, Clouaire T, Guy J, Webb S, Kerr AR, Deaton A, Andrews R, James KD, Turner DJ, Illingworth R, Bird A. (2010).CpG islands influence chromatin structure via the CpG-binding protein Cfp1. Nature. 464(7291):1082-6. PubMed Abstract
Rodoniki Athanasiadou, Dina de Sousa, Kevin Myant, Cara Merusi, Irina Stancheva, Adrian Bird. (2010). Targeting of De Novo DNA Methylation Throughout the Oct-4 Gene Regulatory Region in Differentiating Embryonic Stem Cell. PLoS One. 5(4):e9937 . PubMed Abstract
Skene PJ, Illingworth RS, Webb S, Kerr AR, James KD, Turner DJ, Andrews R, Bird AP.(2010).Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state. Mol Cell.26;37(4):457-68 . PubMed Abstract
Cobb, S., Guy, J. & Bird, A. (2010). Reversibility of functional deficits in experimental models of Rett syndrome. Biochem Soc Trans. 38, 498-506 . PubMed Abstract
Schmiedeberg, L., Skene, P., Deaton, A., Bird, A.(2009). A temporal threshold for formaldehyde crosslinking and fixation. PLoS One 2009;4(2):e4636 PubMed Abstract
Illingworth RS, Bird AP. (2009). CpG islands - 'A rough guide'. FEBS Lett. 2009 Apr 17. [Epub ahead of print] PubMed Abstract
Bird, A. (2008). The methyl-CpG-binding protein MeCP2 and neurological disease. Biochem Soc Trans. 2008 Aug;36(Pt 4):575-83.
PubMed Abstract
Illingworth, R., Kerr, A., Desousa, D., Jørgensen, H., Ellis, P., Stalker, J., Jackson, D,, Clee, C,, Plumb, R., Rogers, J,, Humphray, S., Cox, T., Langford, C., Bird, A. (2008). A novel CpG island set identifies tissue-specific methylation at developmental gene loci. PLoS Biol. 6(1):e22.
PubMed Abstract
Martin V, Jørgensen HF, Chaubert AS, Berger J, Barr H, Shaw P, Bird A, Chaubert P. (2008). MBD2-mediated transcriptional repression of the p14ARF tumor suppressor gene in human colon cancer cells. Pathobiology. 75(5):281-7. PubMed Abstract
Ho, K.L., McNae, I.W., Schmiedeberg L., Klose, R.J., Bird, A.P., Walkinshaw, M.D.(2008). MeCP2 binding to DNA depends upon hydration at methyl-CpG. Mol Cell. 29:525-31
PubMed Abstract
Suzuki, M.M. and Bird, A. (2007). DNA methylation landscapes: provocative insights from epigenomics. Nat. Rev. Genet. 9(6):465-76.
PubMed Abstract
Bird, A. The methyl-CpG-binding protein MeCP2 and neurological disease. (2008).Biochem Soc Trans. 36, 575-83 . PubMed Abstract
Li, E. & Bird, A. DNA methylation in mammals. (2007) "Epigenetics" Editors: Allis, C. D., Jenuwein, T., Reinberg, D. Cold Spring Harbor Press., 341 - 355
Bird, A. (2007). Perceptions of epigenetics.. Nature. 447:396-8.
PubMed Abstract
Bird, A. Q & A: Adrian Bird. Current Biology in press(2007)
Suzuki, M.M., Kerr, A.R., De Sousa, D., Bird, A. (2007). CpG methylation is targeted to transcription units in an invertebrate genome. Genome Res. 17(5):625-31.
PubMed Abstract
Nan X, Hou J, Maclean A, Nasir J, Lafuente MJ, Shu X, Kriaucionis S, Bird A. (2007). Interaction between chromatin proteins MECP2 and ATRX is disrupted by mutations that cause inherited mental retardation. Proc Natl Acad Sci U S A. 104(8):2709-14. PubMed Abstract
Berger, J., Sansom, O., Clarke, A., Bird, A. (2007). MBD2 is required for correct spatial gene expression in the gut. Mol Cell Biol. 11:4049-57.
PubMed Abstract
Barr, H., Hermann, A., Berger, J., Tsai, H.H., Adie, K., Prokhortchouk, A., Hendrich, B., Bird, A.(2007). Mbd2 contributes to DNA methylation-directed repression of the Xist gene. Mol Cell Biol. 27(10):3750-7.
PubMed Abstract
Guy, J., Selfridge, J., Gan, J., Cobb, S. and Bird, A. (2007). Reversal of Neurological Defects in a Mouse Model of Rett Syndrome. Science. 315, 1143-7
Jorgensen, H. F., Adie, K., Chaubert, P., and Bird, A. P. (2006). Engineering a high-affinity methyl-CpG-binding protein. Nucleic Acids Res 34, e96.
PubMed Abstract
Hu K, Nan X, Bird A, Wang W. (2006). Testing for association between MeCP2 and the brahma-associated SWI/SNF chromatin-remodeling complex. Nat Genet. 38(9):962-4;
PubMed Abstract
Klose, R. J., and Bird, A. P. (2006). Genomic DNA methylation: the mark and its mediators. Trends Biochem Sci 31, 89-97.
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Kriaucionis, S., Paterson, A., Curtis, J., Guy, J., Macleod, N., and Bird, A. (2006). Gene expression analysis exposes mitochondrial abnormalities in a mouse model of Rett syndrome. Mol Cell Biol 26, 5033-5042.
PubMed Abstract
Prokhortchouk, A., Sansom, O., Selfridge, J., Caballero, I. M., Salozhin, S., Aithozhina, D., Cerchietti, L., Meng, F. G., Augenlicht, L. H., Mariadason, J. M., et al. (2006). Kaiso-deficient mice show resistance to intestinal cancer. Mol Cell Biol 26, 199-208.
PubMed Abstract
Hutchins, A.S., Artis, D., Hendrich, B.D., Bird, A.P., Scott, P. and Reiner, S.L. (2005). Cutting edge: a critical role for gene silencing in preventing excessive type 1 immunity. J. Immunol. 175: 5606-5610.
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Suzuki, M.M., Nishikawa, T. and Bird, A. (2005) . Genomic changes reveal unexpected divergence within Ciona intestinalis. J. Mol. Evol. 61: 627-635.
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Klose, RJ., Sarraf, SA., Schmiedeberg, L,, McDermott, SM., Stancheva, I and Bird AP. [2005] DNA binding selectivity of MeCP2 due to a requirement for A/T sequences adjacent to methyl-CpG. Mol Cell. 19(: 667-78.
PubMed Abstract
Nuber, UA,. Kriaucionis, S., Roloff, TC., Guy, J., Selfridge, J., Steinhoff, C., Schulz, R., Lipkowitz, B., Ropers, HH., Holmes, MC and Bird. A. [2005] Up-regulation of glucocorticoid-regulated genes in a mouse model of Rett syndrome. Hum Mol Genet. 2005 14: 2247-56
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