Our lab uses a broad range of technologies to answer questions about the role of DNA and chromatin modifications in health and disease. At one extreme we study animal models of the debilitating autism spectrum disorder Rett Syndrome to better understand the origin and potential reversal of this condition. At the other, we engage in high throughput DNA sequencing and molecular structure determination of proteins that read signals on the DNA. This breadth – from molecules to organisms - forces us to see biomedical issues at more than one level and keeps our research at the forefront. We benefit from being embedded within the Wellcome Centre for Cell Biology, which houses research groups studying the fundamental biology of cells and boasts state-of-the-art facilities. The superb range of expertise in biology, medicine and other sciences at Edinburgh University is also a major asset for us.

Adrian Bird, Buchanan Professor of Genetics